22
Sep

Cancer bioinformatics

DR. ERIK FREDLUND

 

 

TEAM LEADER: DR. ERIK FREDLUND

The Translational Cancer Bioinformatics team is focused on functional analyses of omics-type cancer data.

By integrating multiple layers of high-throughput data with a strong knowledge of tumor biology we build hypotheses that can be tested using molecular biology methods. We are continuously developing and improving methods for analysis of deregulated signaling pathways in cancer by merging mutational, copy-number, gene expression, and quantitative proteomics data. We also have extensive experience in developing tools and pipelines for the analysis of microarray and Next-Generation Sequencing transcriptome and genome data. We are applying our developed methods to study human breast cancer subtypes as well as tumor development in mouse models of human cancer. We also have a strong focus on developing methods for rational selection of treatment for cancer patients based on tumor omic and phenotypic features.

 

Team Members : 

Erik Fredlund, PhD, Assistant Professor 

Jorrit Boekel, PhD, Scientific Programmer

Oliver Frings, PhD, Postdoc

Alejandro Fernandez Woodbridge, PhD, Postdoc

Yafeng Zhu, MSc, PhD-student

John Siavelis, MD, MSc, PhD-student

Taner Arslan, MSc, PhD-student