Splice variant analysis in shotgun proteomics

Zhu Y et al. MCP 2014

 

 

SpliceVista is a bioinformatic tool which enables splice variants analysis and visualization in shotgun proteomics.

More than 90% of human genes have alternatively spliced products, gene centric analysis omits differential regulation of splice variants. Illustrated in the above figure.

 (Red peptides are Isoform A specific peptides, black ones are shared between two isoforms)

Published in Mol. Cell Proteomics 2014 Jun;13(6):1552-62 PubMed link  

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Download at Github https://github.com/yafeng/SpliceVista/